Xeljanz (tofacitinib) prescription available online
If you suffer from rheumatoid arthritis, psoriatic arthritis, or ulcerative colitis, Xeljanz can help. Get a new prescription or refill of Xeljanz from a board-certified doctor online.
Book an appointment
Medication services available for adults and kids (3+)
Top-quality, board-certified doctors
Insurance accepted, but not required
Prescriptions sent to your local pharmacy*
*Prescriptions provided at the doctor’s discretion
Most major insurance plans accepted
Most patients with in-network insurance pay $30 or less. Paying without insurance? New patient visits are $129, and follow-ups are only $99 for members.
Don’t see your provider listed? Email [email protected] or call (888) 564-4454 to talk to a PlushCare specialist.
3 simple steps to request your Xeljanz prescription today
Step 1
Book a Xeljanz prescription request appointment.
Book a same day appointment from anywhere.
Step 2
Talk to your medical provider regarding your Xeljanz prescription.
Visit with a doctor on your smartphone or computer.
Step 3
Pick up your Xeljanz prescription.
We can send prescriptions to any local pharmacy.
Xeljanz prescription pricing details
How pricing works
To get a new or refill on your Xeljanz prescription, join our monthly membership and get discounted visits.
Paying with insurance
Membership
$14.99/month
First month free
First visit
Copay
For all visits
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price with insurance
Often the same as an office visit. Most patients with in-network insurance pay $30 or less!
- We accept these insurance plans and many more:
Paying without insurance
Membership
$14.99/month
First month free
First visit
$129
Repeats only $99
30 days of free membership
Same-day appointments 7 days a week
Unlimited messages with your Care Team
Prescription discount card to save up to 80%
Exclusive discounts on lab tests
Free memberships for your family
Cancel anytime
Visit price without insurance
Initial visits are $129 and follow-ups are only $99 for active members.
If we're unable to treat you, we'll provide a full refund.
Xeljanz prescription FAQs
How much does Xeljanz cost?
Depending on your pharmacy, Xeljanz 5 mg costs around $5,486 for 60 tablets. Fortunately, generic brands, such as tofacitinib, offer an affordable alternative.
How can I refill my Xeljanz prescription?
To refill your Xeljanz prescription, book a virtual appointment with one of our top rated board-certified doctors. After reviewing your symptoms and medical history, your doctor can send an electronic prescription to your local pharmacy.
Who should not take Xeljanz?
Avoid taking Xeljanz if you have certain medical conditions, such as:
Chronic or recurrent infection
Are a current or past smoker
Any type of cancer, including skin cancer, lung cancer, and lymphoma
Liver disease or kidney disease
Allergic reactions to tofacitinib
A weakened immune system due to chronic lung disease, diabetes, or HIV
Risk factors for major adverse cardiovascular events, such as high blood pressure
Does Xeljanz make you tired?
Yes, fatigue is a possible side effect of Xeljanz and Xeljanz XR tablets.
Does Xeljanz affect mood?
No, mood changes are not a side effect of Xeljanz.
Can you drink alcohol with Xeljanz?
Talk to your doctor before drinking alcohol. Drinking alcohol while taking Xeljanz may lead to an increased risk of adverse effects, such as liver problems.
What happens if I miss a dose of Xeljanz?
If you miss a dose of Xeljanz, take the missed dose as soon as you remember. Skip the missed dose if it's almost time for your next dose. Avoid taking two doses to make up for a missed dose.
What happens if I take too much Xeljanz?
If you've taken too much Xeljanz, Xeljanz XR, or Xeljanz oral solution, seek emergency medical help or contact your local poison control center.
About Xeljanz
Xeljanz is a disease-modifying anti-rheumatic drug (DMARD) that belongs to a group of drugs known as Janus kinase (JAK) inhibitors. It functions by interrupting specific signaling pathways and suppressing the immune system.
Some conditions that Xeljanz is known to treat include rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Xeljanz is available only by prescription. It is available in a generic formulation as well as under different brand names, including tofacitinib.
Xeljanz may be prescribed as a tablet, oral solution, or extended-release tablet. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage prescribed.
If you're prescribed Xeljanz, be sure to complete the full course of the JAK inhibitor unless your doctor specifically tells you to stop. If you don’t complete your prescription, the JAK inhibitor may not fully treat your rheumatoid arthritis, psoriatic arthritis, or ulcerative colitis.
Xeljanz uses
There are several FDA-approved uses for Xeljanz, but your healthcare provider may also prescribe it off-label to treat other medical conditions.
Your PlushCare doctor may prescribe Xeljanz for any of the following reasons, or other reasons not listed here. If you have questions about why a medication is prescribed, ask your online doctor or pharmacist.
Rheumatoid arthritis
Xeljanz is FDA-approved to treat moderately to severely active rheumatoid arthritis in adults who have an inadequate response to methotrexate.
Psoriatic arthritis
Xeljanz is FDA-approved to treat active psoriatic arthritis in adults who have an inadequate response to methotrexate.
Ulcerative colitis
Xeljanz is FDA-approved to treat adults with severely active ulcerative colitis.
Xeljanz side effects
The side effects associated with taking Xeljanz are typically mild. Most Xeljanz side effects are related to upper respiratory tract infections.
Xeljanz has some common side effects. They may include:
Upper respiratory tract infections (common cold, sinus infections)
Headache
Nausea
Other side effects, which are less common but might be more severe, could include:Serious infections
Cancer and immune system problems
Increased risk of major adverse cardiovascular events
You should call your doctor if you notice any of these side effects, or if you develop any other new or concerning symptoms. Xeljanz can increase your risk of developing infections, including urinary tract infection (UTI), upper respiratory tract infection, and skin infection.
Xeljanz may be used in young children over two years of age to treat polyarticular course juvenile idiopathic arthritis.
How to take Xeljanz
Your pharmacist will provide you with instructions on how to take your Xeljanz prescription. Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.
Xeljanz can come in different forms and doses, so be sure to follow the specific instructions on your prescription. The starting dose is typically Xeljanz 5 mg twice daily for arthritis and Xeljanz 10 mg twice daily for ulcerative colitis. Your doctor may adjust your dosage if you have severe renal impairment or moderate hepatic impairment.
Xeljanz is typically taken twice a day with or without food, while Xeljanz XR tablets are taken once daily with or without food. Follow your healthcare provider's instructions throughout Xeljanz treatment.
What to avoid while taking Xeljanz
Xeljanz has 531 drug interactions. Don’t change what you are taking without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs.
Possible drug interactions with Xeljanz include:
Other medications used to treat rheumatoid arthritis, psoriatic arthritis, or ulcerative colitis
Other immunosuppressive drugs
Medicines that affect the way liver enzymes function
Tell your doctor if you're taking any other immunosuppressive drugs or if you notice any signs of an infection. Epstein Barr Virus-associated post-transplant lymphoproliferative disorder has been observed in renal transplant patients treated with Xeljanz and concomitant immunosuppressive medications.
Talk to your doctor before drinking alcohol. Drinking alcohol while taking Xeljanz may lead to an increased risk of liver damage.
Medication alternatives to Xeljanz
If your healthcare provider prefers to put you on another treatment, they may suggest other JAK inhibitors or tumor necrosis factor inhibitors in another drug class. Here are some common doctor-recommended alternatives based on your health issue:
Rheumatoid arthritis
Psoriatic arthritis
Rinvoq (upadacitinib)
Humira (adalimumab)Ulcerative colitis
Humira (adalimumab)Rinvoq (upadacitinib)