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COVID medications available online

Learn how COVID medications can help shorten the duration of COVID-19 symptoms and infection with a consultation from one of our board-certified doctors online. Get a prescription for COVID medications from a top-rated doctor online.*

Book an appointment

Online same day doctor appointment booking

Top quality, board-certified doctors

Insurance accepted, but not required

Save up to 80% on your prescriptions* with RX discount card

*Prescriptions are provided at the doctor’s discretion. You may qualify for antiviral therapy if you are: within 5 days of experiencing mild to moderate COVID symptoms, confirmed to be COVID-19 positive via PCR or rapid antigen test, and felt to be at high risk of complications from COVID-19 infection. Learn more about our controlled substances policy and our prescription discount card.

Most major insurance plans accepted

Most patients with in-network insurance pay $30 or less. Paying without insurance? New patient visits are $129, and follow-ups are only $99 for members.

Don’t see your provider listed? Email [email protected]  or call  (888) 564-4454  to talk to a PlushCare specialist.

3 simple steps to getting COVID medication online

Step 1: Book an appointment

Step 1

Book an appointment to discuss COVID medication.

Book a same day appointment from anywhere.

Step 2: Visit with a doctor on your smartphone

Step 2

Talk to your doctor online about COVID medication.

See a doctor on your smartphone or computer.

Step 3: pick up at local pharmacy

Step 3

Pick up your COVID medication, if prescribed.

Prescriptions are provided based on eligibility. We can send COVID medication to any local pharmacy.

COVID medication pricing details

How pricing works

To get COVID medications online, join our monthly membership and get discounted visits.

Paying with insurance

Membership

$14.99/month

First month free

First visit

Copay

For all visits

30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • United Healthcare

Paying without insurance

Membership

$14.99/month

First month free

First visit

$129

Repeats only $99

30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129 and follow-ups are only $99 for active members.

Book an appointment

If we're unable to treat you, we'll provide a full refund.

COVID medication FAQs

  • What medications can I take to relieve the symptoms of COVID-19?

    Paxlovid and molnupiravir have been shown to decrease the duration of symptoms in COVID-19 patients. They are oral antiviral pills that can be taken at home if you are confirmed to be COVID-19 positive via testing. Book an appointment with one of our board-certified physicians today if you're experiencing symptoms of COVID to see if you qualify for medication.

  • How can I get COVID pills?

    The COVID-19 pill is only available with a prescription. If you are within five days of experiencing mild to moderate COVID symptoms, are confirmed to be COVID-19 positive via a PCR or rapid antigen test, and are deemed to be at high risk, one of our board-certified doctors can prescribe you the COVID-19 pills to take at home. To request the COVID-19 pill and find out if you qualify for a prescription, book an appointment with one of our trusted, board-certified doctors today.

  • How should I take COVID medications?

    Molnupiravir, Paxlovid, and remdesivir are three different antiviral drugs used to treat COVID-19, and they are taken in different ways. Here is a brief overview of how each of these drugs is taken:

    • Molnupiravir (Lagevrio) is an oral medication that is taken twice daily with food for five days. It can be taken at home.

    • Paxlovid is a combination of two drugs, nirmatrelvir and ritonavir, that are taken orally. The medication is taken twice daily for five days, and should be taken with food. It can also be taken at home.

    • Remdesivir is an intravenous medication that is given to hospitalized patients with severe COVID-19. The medication is given via IV infusion for five to ten days, depending on the severity of symptoms.


    It's important to note that these drugs are not a cure for COVID-19, and their effectiveness can vary depending on the stage and severity of the disease. The specific instructions for taking these medications may vary depending on the advice of your doctor.

  • Who shouldn’t take COVID medications?

    There are different types of COVID medications, and the specific reasons why someone should not take them may vary depending on the medication and the individual's medical history. However, here are some common reasons why someone should not take COVID medication:

    • Allergy or intolerance

    • Medication interactions: Some medications may interact with COVID antivirals, which can cause side effects or make the medications less effective. It's important to let your healthcare provider know about all medications you are taking, including over-the-counter medications, vitamins, and supplements, to avoid potential interactions.

    • Medical conditions: Some medical conditions, such as liver or kidney disease, may affect how the medication is processed by the body. Individuals with heart conditions may be at risk of developing complications from taking COVID medication as well.

    • Pregnancy or breastfeeding: Some COVID medication may not be safe to take during pregnancy or while breastfeeding. It's important to let your healthcare provider know if you are pregnant or breastfeeding before taking them.

    • Age: Some medications may not be appropriate for certain age groups. For example, remdesivir, an antiviral medication given via IV, is only authorized for use in adults and children over 12 years of age who weigh at least 88 pounds.

  • How long does it take for COVID medications to work?

    The length of time it takes for COVID medications to work can vary depending on the specific medication, the stage and severity of the disease, and the individual's overall health. In general, clinical trials have suggested that molnupiravir and Paxlovid can start to work within a few days of starting treatment.

    Remdesivir is an intravenous medication that is given to hospitalized patients with severe COVID-19 for five to ten days, depending on the severity of the disease. Clinical trials have shown that patients who received remdesivir had a median recovery time of 10 days, compared to 15 days for those who received a placebo.

    It's important to note that the effectiveness of these medications can vary depending on several factors, including the timing of treatment and the severity of the disease.

  • What should I avoid with COVID medications?

    The specific instructions for COVID medications may vary depending on the medication and the advice of your doctor. However, here are some general guidelines to follow when taking COVID medications:

    • Avoid alcohol: Alcohol can interfere with the effectiveness of some medications and can also cause side effects. It's generally recommended to avoid alcohol when taking COVID medications.

    • Follow food instructions: Some COVID medications may need to be taken with food or avoid certain foods.

    • Follow storage instructions: COVID medications may have specific storage requirements, such as being kept in a refrigerator or avoiding exposure to light.

    • Avoid medications with drug interactions: Some medications, such as high cholesterol medications, high blood pressure medications, migraine medications, antipsychotics, and erectile dysfunction medications can interact with COVID antivirals.

  • Can vaccinated individuals get the COVID-19 pill?

    Yes, anyone with mild to moderate COVID symptoms can take the COVID-19 pill within the first five days of symptom onset, to reduce severity of symptoms. Your doctor will ask to see your COVID-19 test results, prior to prescribing the COVID-19 pill.

  • Can I use the COVID-19 pill instead of getting vaccinated?

    The COVID-19 pill is not a substitute for getting vaccinated. The most effective way to prevent COVID-19 and its spread is to get vaccinated. Although vaccinated individuals can still get COVID-19, the COVID-19 pill will have the best outcomes for vaccinated individuals.

  • Is there an antiviral treatment for COVID-19?

    Previously, there was only one antiviral for COVID approved by the FDA, which is the antiviral drug remdesivir. Remdesivir can only be given to COVID-19 patients intravenously in a hospital setting.

    However, two pharmaceutical companies have developed oral medications to treat COVID-19 in outpatients. The Pfizer COVID pill, with brand name Paxlovid, is taken in combination with another antiviral, ritonavir, after experiencing COVID-19 symptoms. It also has the potential to be taken after known exposure to COVID-19.  Merck also received  FDA approval for a new antiviral drug, molnupiravir, an oral pill that can be taken shortly after experiencing COVID-19 symptoms.

    The release of both new COVID pills could help keep patients out of the hospital, as the medications can be taken at home.

  • What were the results of the COVID-19 pill clinical trials?

    Merck and Ridgeback Biotherapeutics released results of their Phase 3 clinical trial to determine the effectiveness of their COVID-19 pill, molnupiravir. 775 adults were evaluated in the clinical trial, all of whom had mild to moderate COVID symptoms, were at high risk for severe disease, and were unvaccinated. Merck decided to conduct the trial in unvaccinated patients to determine how well the pill would prevent hospitalization and death.

    Only 7.3% of patients taking the antiviral for COVID were hospitalized or died after 30 days, compared to 14.1% of patients who did not receive molnupiravir. An independent committee monitoring the trial found the results so hopeful that they recommended ending the trial early.

    Pfizer announced the results of Phase 2 of a 3-phase clinical trial to determine the effectiveness of Paxlovid. They evaluated 1219 adults, all of whom had mild to moderate COVID-19 symptoms, and who had at least one factor that put them at high risk for severe illness, and were unvaccinated.

    Paxlovid, shows promise, as it was found to reduce the risk of death or hospitalization by 89%. Only 0.8% of patients who took the COVID 19 pill were hospitalized or died after 28 days, compared to 7% of patients who did not receive Paxlovid. The results of Pfizer’s trial were so promising, that the trial ended early. According to these results, Paxlovid seems to be more effective than molnupiravir. This data led the FDA to approve the use of Paxlovid under an Emergency Use Authorization.

    Although the effectiveness of the drugs was only evaluated in unvaccinated patients, it is possible that vaccinated COVID-19 patients who are treated with the COVID-19 pill would experience even greater effectiveness. Experts continue to recommend that everyone get vaccinated against COVID-19. The benefits are felt to be additive, meaning that the vaccine in combination with the new antiviral treatment would produce even greater protection against severe COVID-19 symptoms, especially in patients who are at the highest risk of severe disease and death.

About COVID medications

COVID medications, also called COVID pills or COVID antivirals, are a class of drugs that are designed to specifically target the SARS-CoV-2 virus, which is responsible for causing COVID-19. These drugs work by interfering with the replication of the virus, either by directly inhibiting the virus itself or by modulating the host immune response.

The COVID-19 pills are treatments for COVID-19 that can be taken at home to treat mild to moderate COVID-19 symptoms. Both the Pfizer COVID-19 pill, Paxlovid, and the Merck COVID-19 pill, molnupiravir, are FDA authorized and currently the only medications for COVID that can be taken at home, rather than in a hospital.

Paxlovid is a combination of two antiviral medications, ritonavir and nirmatrelvir, that work together to block the replication of the virus. Three Paxlovid pills are taken twice daily for a total of five days. Each carton contains 30 tablets divided in five daily-dose blister cards.

Molnupiravir is another oral antiviral medication that also works by blocking the replication of the COVID-19 virus, which can help reduce the risk of serious illness. Molnupiravir is taken twice a day, for five days.

Both Paxlovid and molnupiravir must be taken within five days of COVID symptom onset in order to be effective.

One of the most well-known antiviral drugs used for COVID-19 treatment is remdesivir, which was initially developed for the treatment of Ebola. Remdesivir works by blocking the replication of the virus by inhibiting the activity of an enzyme that is necessary for viral replication. This reduces the amount of virus in the body, and therefore, can potentially lessen the severity and duration of COVID-19 symptoms. Remdesivir can only be given in a healthcare facility because it must be administered by a licensed provider via intravenous infusion. You must begin remdesivir within seven days of symptom onset in order for it to be effective.

Types of COVID medications available online

There are two types of medications for COVID available: oral antiviral medications and other antivirals.

  • Oral antivirals

    If you test positive for COVID-19, these oral antiviral pills can be taken in the comfort of your home to lessen the severity and duration of COVID symptoms.

    Paxlovid (nirmatrelvir / ritonavir)

    Molnupiravir (Lagevrio)

  • Other antiviral medications

    Other antiviral treatment options, such as remdesivir, must be administered via IV in a hospital setting.

How COVID medications work

COVID-19 medications work by blocking how the SARS-CoV-2 virus replicates. Without being able to replicate, the COVID-19 virus dies. However, Paxlovid, molnupiravir, and remdesivir block viral replication in different ways.

  • Molnupiravir (Lagevrio) is an antiviral drug that works by blocking how the SARS-CoV-2 virus copies itself. COVID-19 uses RNA to replicate. Molnupiravir adds itself into the virus’s RNA while the virus copies itself, creating mutations in the virus’s genetic code.

    When the COVID-19 virus attempts to create viral proteins from this mutated RNA, the result is that these proteins have too many mutations to function. The virus dies after accumulating enough mutations. In addition, these mutations accumulate randomly, making it more difficult for the COVID-19 virus to eventually develop resistance to molnupiravir.

    Paxlovid (nirmatrelvir/ ritonavir) is an antiviral drug that works by blocking a different step of the SARS-CoV-2 replication process. In order for the RNA to begin copying itself, certain protein bonds must be broken, a step called proteolysis. Paxlovid's component, nirmatrelvir, blocks this step, so that the viral RNA cannot replicate.

    The other component of Paxlovid, ritonavir, slows down the breakdown of Pfizer’s antiviral in the body. The result is that Paxlovid is able to remain in the body for a longer amount of time, making it more effective.

    Remdesivir is another antiviral drug that works by inhibiting the replication of the SARS-CoV-2 virus. However, it does so by targeting an enzyme called RNA-dependent RNA polymerase (RdRp), which is necessary for the virus to replicate its genetic material.

    By inhibiting viral replication, remdesivir can reduce the severity of COVID-19 and prevent the virus from spreading throughout the body.

    Remdesivir is administered intravenously over a period of several days in a hospital setting.

Side effects of COVID medications

Many people will have no side effects from COVID medications. However, they can cause some common side effects.

  • Side effects of Paxlovid include:

    • Allergic reactions

    • An altered or impaired sense of taste

    • Diarrhea

    • Muscle aches

    • Increased blood pressure

    • Liver damage (People with existing liver problems may have a higher risk of this serious side effect.)


    Common side effects of remdesivir include:

    • Nausea and vomiting

    • Puffiness or swelling of the eyes, face, lips, or tongue


    Common side effects of molnupiravir include:

    • Diarrhea

    • Nausea

    • Dizziness


    Speak to a doctor immediately if you experience any severe or life-threatening side effects, including allergic reactions.

COVID medication risks

COVID medications are generally safe, but there are some risks if you have other medical conditions or take certain medications.

  • One of the major concerns about molnupiravir is the potential for birth defects. Because this pill works by changing the way RNA is copied, there is a possibility that it could cause mutations during fetal development. Due to this potential risk, the molnupiravir clinical trial was not conducted in any pregnant  or breastfeeding women. However, Daria Hazuda, Merck’s vice president of infectious disease discovery and chief science officer is confident that, “the drug will be safe if used as intended.”

    Patients with hemophilia, hepatotoxicity, hyperglycemia, hyperlipidemia, or a heart block should use Paxlovid with caution and let their doctor know if they have any of these conditions.

    Remdesivir has the potential to cause kidney or liver damage, so be sure to tell your doctor if you have any heart, liver, or kidney-related conditions.

    COVID medication drug interactions 

    When you begin a new medication, make sure to tell your doctor about any other medications, supplements, or herbs you’re taking. Many medications and supplements have the potential to cause drug interactions with COVID antivirals.

    Common examples of medications that may interact with Paxlovid are:


    There are several drugs known to interact with remdesivir. Common examples include:


    Molnupiravir does not have many noted drug interactions, but it may interact with other drugs similarly to the other antivirals noted above.

PlushCare online COVID medications ratings and reviews

Our online doctors have treated over 550,000 patients.