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Effexor (venlafaxine) prescription available online

If you are living with depression, general anxiety disorder, social anxiety disorder, or panic disorder, Effexor can help. Get a new prescription or refill of Effexor today from a board-certified doctor online.

Book an appointment

Medication services available for adults and kids (3+)

Top quality, board-certified doctors

Insurance accepted, but not required

Prescriptions sent to your local pharmacy*

*Prescriptions provided at the doctor’s discretion.

Most major insurance plans accepted

Most patients with in-network insurance pay $30 or less. Paying without insurance? New patient visits are $129, and follow-ups are only $99 for members.

Don’t see your provider listed? Email [email protected]  or call  (888) 564-4454  to talk to a PlushCare specialist.

3 simple steps to request your Effexor prescription today

Step 1: Book an appointment

Step 1

Book an Effexor prescription request appointment.

You can book a same-day appointment from anywhere.

Step 2: Visit with a doctor on your smartphone

Step 2

Talk to your medical provider regarding your Effexor prescription.

You can visit a doctor on your smartphone or computer.

Step 3: pick up at local pharmacy

Step 3

Pick up your Effexor prescription.

We can send prescriptions to any local pharmacy.

Effexor prescription pricing details

How pricing works

To get a new or refill on your Effexor prescription, join our monthly membership and get discounted visits.

Paying with insurance



First month free

First visit


For all visits

30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price with insurance

Often the same as an office visit. Most patients with in-network insurance pay $30 or less!

  • We accept these insurance plans and many more:

    • Humana
    • Aetna
    • United Healthcare

Paying without insurance



First month free

First visit


Repeats only $99

30 days of free membership

  • Same-day appointments 7 days a week

  • Unlimited messages with your Care Team

  • Prescription discount card to save up to 80%

  • Exclusive discounts on lab tests

  • Free memberships for your family

  • Cancel anytime

Visit price without insurance

Initial visits are $129 and follow-ups are only $99 for active members.

Book an appointment

If we're unable to treat you, we'll provide a full refund.

Effexor prescription FAQs

  • How much does Effexor cost?

    The typical cost of Effexor is $490 for a supply of 30 capsules of 37.5 mg. This price will fluctuate depending on insurance and the pharmacy.

  • How can I refill my Effexor prescription?

    A doctor or pharmacist can refill Effexor. It can be picked up from any local pharmacy.

  • What should I avoid while taking Venlafaxine? 

    Effexor should not be taken with or within 2 weeks of monoamine oxidase inhibitors. You should not take serotonin medication without asking your doctor for medical advice. Effexor may increase the effects of other medications that can cause bleeding, including aspirin and Advil.

  • How long does it take to get used to Effexor?

    It takes about 3 days for Effexor to remain consistent in your bloodstream. Also, any side effects may taper off after the first couple weeks.

  • What time of day is it best to take Effexor?

    There is no set time to take Effexor XR. Just make sure to take it at the same time every day. If you have trouble sleeping, take Effexor in the morning.

  • What are the dangers of taking Effexor?

    While Effexor is ideal for treating panic disorder, generalized anxiety disorder, depression, and social anxiety disorder, there is a risk of serious side effects, including:

    • Suicidal thoughts

    • Serotonin syndrome

    • High blood pressure

    • Closed-angle glaucoma

    • mania or hypomania

    • Allergic reaction

    • Low blood sodium

    • Seizures

    • Pneumonia

    • High cholesterol

  • Who should not take Effexor?

    • People with a history of brain disease, damage, or seizures as this can increase the risk.

    • Heart disease or high or low blood pressure, as Effexor can make these worse.

    • History of mania as Effexor can make this worse.

    • Kidney disease or liver disease as these can increase adverse side effects

  • What happens if I miss a dose of Effexor?

    Take the missed dose of Effexor as soon as possible; however, if it is close to your next dose, you can skip and take your scheduled dose.

  • What happens if I take too much Effexor?

    Small overdosing can cause nausea, serotonin syndrome, vomiting, anorexia, drowsiness, tremors, anxiety, tachycardia, and changes in blood pressure. Large overdoses can cause delirium, seizures, and coma. As with any prescription medicine, call your local poison control center or doctor for medical advice as soon as the overdose happens.

About Effexor

Effexor is part of a group of selective serotonin and norepinephrine reuptake inhibitors (SNRIs), which function by adjusting unbalanced chemicals in the brain. Like any elective serotonin and norepinephrine reuptake inhibitor, this medication can only be used for depression and anxiety. It is ineffective against other mental conditions because it will not adjust those chemicals.

Some conditions that Effexor is known to treat include depression, generalized anxiety disorder, panic disorder, bipolar disorder, and social anxiety disorder. Effexor is available only by prescription. It is available in a generic formulation under brand names, including Venlafaxine and Effexor XR.

Effexor may be prescribed as immediate-release or extended-release tablets and capsules. It’s always important to follow the specific instructions on your prescription, as they can vary based on the formulation and dosage you are prescribed.

If you are prescribed Effexor, be sure to complete the selective serotonin and norepinephrine reuptake inhibitor course unless your doctor specifically tells you to stop.

If you don’t complete your prescription, the antidepressant may not fully treat your depression and anxiety.

Effexor uses

There are 4 FDA-approved uses for Effexor, but it may also be used off-label to treat other conditions. Your online medical professional may prescribe it for any of the following common reasons. It’s also possible that your healthcare provider may prescribe it for other reasons not listed here. Ask your online doctor or pharmacist if you have questions about why a medication is prescribed.

  • Major depressive disorder (MDD)

    Major depressive disorder is described as sadness and hopelessness that don't go away.

  • Generalized anxiety disorder

    Generalized anxiety disorder causes patients to worry more than normal. Including preventing normal day-to-day activities, trouble focusing, and rapid heartbeat.

  • Social anxiety disorder (SAD)

    Social anxiety disorder causes people to worry about any interactions with people. This includes social situations like meeting new people or going to crowded locations.

  • Panic disorder

    Panic disorder causes sudden panic attacks or intense feelings of fear and discomfort.

Effexor side effects

  • The side effects associated with taking Effexor are typically mild. Most Effexor side effects are related to physical discomfort. Effexor has some common side effects. They may include:

    • Headache

    • Dizziness

    • Drowsiness

    • Tiredness

    • Sleep trouble

    • Sexual dysfunction

    • Changes in weight

    • Fast heartbeat

    Other side effects, which are less common but might be more severe, could include:

    • Symptoms of serotonin syndrome include hallucinations, sweating, twitching, nausea, vomiting, or diarrhea.

    • Blurred vision

    • Seizure

    • Difficulty breathing

    • Unusual bleeding problems

    • Low blood sodium

    • Severe nervous system reaction

    You should call your doctor if you notice any of these side effects or develop other new or concerning symptoms. Use of Effexor in young children under age 12 is not advised because it is not approved by the FDA for child use.

How to take Effexor

Your pharmacist will provide you with instructions on how to take your Effexor prescription.

Be sure to read your prescription label and follow the instructions. Call your doctor or pharmacy if you have any questions.

Effexor can come in different forms and doses, so follow the specific instructions on your prescription. It is typically prescribed one time per day. Some specific instructions may include; Extended release: 75 mg orally once daily.

What to avoid while taking Effexor

Effexor has 662 drug interactions. Don’t change what you take without checking with your doctor or pharmacist. That includes other medications or supplements, as well as over-the-counter drugs. 

Ask your doctor when taking Effexor before taking any opioid medications, sleeping pills, muscle relaxers, or seizure medication.

Ask your doctor or pharmacist if it is acceptable to consume alcohol while taking Effexor.

Some research shows that regular alcohol consumption may increase nervous system side effects, including dizziness and drowsiness. Alcohol may also reduce the medication’s ability to do its job, making it harder to treat depression and anxiety.

Avoid taking MAO inhibitors, as these can cause severe and possibly fatal drug interactions.

Tell your doctor before stopping Effexor XR treatment, as this can increase the withdrawal symptoms and worsen the generalized anxiety disorder or depression.

Medication alternatives to Effexor

If your healthcare provider prefers to put you on another treatment, they may suggest another selective serotonin and norepinephrine reuptake inhibitor or an antidepressant in another drug class. Here are some common doctor-recommended alternatives based on your health issue: